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Zyban

Zyban (bupropion) is an oral prescription drug that helps patients quit smoking. Zyban is sold in tablet form.

How Zyban Works
Zyban helps you quit smoking by reducing cravings for nicotine and easing the withdrawal symptoms. Its active ingredient, bupropion, is also used as an anti-depressant.

Advantage of Zyban
People taking Zyban generally stop smoking during the second week of their treatment. Unlike other products that help people quit smoking, Zyban contains no nicotine. This means patients can stop taking Zyban at the end of their treatment without any withdrawal effects. It also means Zyban can be used along with nicotine replacement products like patches or gum, but only under a doctor's supervision.

Studies show that more than 1/3 of people taking Zyban quit smoking for at least a month. More than 1/5 of them quit smoking for at least a year.

How to Take Zyban
Swallow Zyban tablets whole. Do not crush or chew them or the sustained activity of Zyban will be destroyed and the chances of side effects occurring may be increased. Take as directed, usually twice daily for 7 to 12 weeks. Do not take more or less Zyban than prescribed. Since Zyban can cause sleeplessness at first, it is best not to take it near bedtime. It is advised to continue smoking for the first week after starting Zyban until the drug reaches higher levels in your blood. You should quit smoking in the second week on Zyban. Do not smoke if using any nicotine products with Zyban as too much nicotine can cause serious side effects. Do not stop taking Zyban without notifying your doctor.

Zyban Side Effects
Zyban is generally well tolerated. Dry mouth, headache, increased sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision may occur. If these effects persist or worsen, notify your doctor. Report promptly: unusual weight loss or gain, palpitations, agitation, trouble sleeping. Unlikely but report promptly: tremor, dizziness, fainting, mood changes, slowed movements, difficulty urinating, decreased sex drive, drowsiness. Very unlikely but report promptly: seizures, mental problems, fever, muscle aches, yellowing of the eyes or skin. In the unlikely event you have an allergic reaction to Zyban seek medical attention immediately.

Zyban Precautions
Tell your doctor your medical history, especially of: seizures, head injury, brain tumor, heart disease, liver problems, kidney problems, eating disorder, any mental conditions, diabetes, alcohol dependence, and allergies. Because Zyban may make you dizzy and affect coordination, do not drive or operate machinery until you get used to the drug's effects. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking Zyban may increase the risk of having seizures. Suddenly stopping certain tranquilizers is not recommended because doing so may increase the risk of seizures. Elderly patients may be more sensitive to the effects of Zyban Tell your doctor if you are pregnant or plan to become pregnant before taking Zyban. Zyban passes into breast milk so breast-feeding while taking Zyban is not recommended.

Drug Interactions
Before taking Zyban tell your doctor of all nonprescription and prescription medications you use especially: MAO inhibitors (e.g. isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline, linezolid, furazolidone), levodopa, ritonavir, corticosteroids (e.g. prednisone), sedatives, adrenaline-like stimulants (e.g. ephedrine), products containing nicotine. Also report use of drugs which might increase seizure risk such as: phenothiazines (e.g. chlorpromazine), tricyclic antidepressants (e.g. amitriptyline), isoniazid (INH), theophylline. Excess caffeine intake can increase the chance of seizures with Zyban. Check all drug labels for caffeine. Other products used to help quit smoking may contain bupropion, the generic name for Zyban. Do not take bupropion products while using Zyban. Do not start or stop any medicine without doctor or pharmacist approval.